Search A Proteome

Use a PoPS specificity model to search an entire proteome for possible targets of your protease. Is your favourite organism missing from this page? Send an email request to Sarah Boyd ( Alternatively, use this page to search for targets in a fasta file.

Please note that results are only kept on the server for 72 hours.

Your email address, where the results will be sent:

The protease specificity model:

Select the organism (proteome):
Homo sapiens (human):     29,572 proteins
Saccharomyces cerevisiae (baker's yeast):     5,877 proteins
Escherichia coli K12:    10,667 proteins¶ 
Drosophila melanogaster (fruit fly):    19,620 proteins¶ 
Arabidopsis thaliana (thale cress):    30,622 proteins¶ 
Rattus norvegicus (Norway rat):    24,115 proteins¶ 
Mus musculus (house mouse):    56,950 proteins¶ 
Danio rerio (zebrafish):    30,556 proteins¶ 
Plasmodium falciparum (malaria):    5,270 proteins¶ 
Rhadinovirus Human herpesvirus 8:    82 proteins¶ 
Schistosoma mansoni (Blood fluke):    12 proteins¶ 

¶ Derived from the RefSeq database (NCBI): last updated on the 26th March 2006.

Select the preferred score threshold option:
Note: reasoning tables are limited to the top 5 sites in each protein, regardless of the score threshold. See here for more details.
Set the score threshold value to    (any valid floating point number)
Set the score threshold to the maximum score in each substrate
Set the score threshold to the minimum score (all predictions in each substrate except -Infinity)